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Hasil penelitian wajib disertai sosialisasi

Publikasi Penelitian Dosen

Acute and subchronic toxicity of potential ethylacetate fraction of propolis
Abstrak

Propolis from Indonesia is widely used in traditional medicine and is reported to have a broad spectrum of pharmacological activities. However nothing is known
about its toxicity. The objective of this study was to evaluate the acute and subchronic toxicity of the potential ethylacetate extract of Indonesian propolis in mice.
The acute toxicity LD50 was estimated to be 14,8597g/kgBW. In the subchronic toxicity, there was no mortality recorded among the animals when varyng doses
of the fraction (500 and 1000mg/kg-1body weight) were administered orally for 36 days consecutively. The weekly body weight of the mice showed no significant
differences between the control and the mice treated with the fraction except on the last week (day 36). There was neither any gros lession nor histopathological
changes observed in organs examined. These finding suggest that the fraction of propolis could be relatively safe when administered orally in mice.

Penulis : SYAMSUDDIN , Prof. Dr. M.Biomed. [PDF File] didownload : 45 x

Uji Toksisitas Subkronik Ekstrak Eatanol Kulit Batang Jaloh (Salix tetrasperma Roxb) Terhadap Parameter Fungsi dan Gambaran Histopatologi Organ Ginjal Tikus
Abstrak

Uji Toksisitas Subkronik Ekstrak Eatanol Kulit Batang Jaloh (Salix tetrasperma Roxb) Terhadap Parameter Fungsi dan Gambaran Histopatologi Organ Ginjal Tikus

Ros Sumarny, Sugito, Eko, Andri